Product documentation
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NAD+ 500mg - nicotinamide adenine dinucleotide, a redox coenzyme studied for sirtuin activity, PARP signaling and cellular energy research.
Research Use Only:This compound is intended exclusively for in vitro laboratory research applications. Not for human or veterinary consumption.
NAD+ research overview
NAD+ is nicotinamide adenine dinucleotide in its oxidised form, a coenzyme present in every living cell and central to redox chemistry. It shuttles electrons through glycolysis, the citric acid cycle and oxidative phosphorylation, which alone would make it a standard laboratory reagent. Its place in current research literature comes from a second role.
NAD+ is consumed, not merely recycled, by three enzyme families: the sirtuins, the PARPs involved in DNA damage response, and CD38. Because those enzymes cleave the molecule rather than returning it, cellular NAD+ concentration acts as a signal about metabolic and genomic state. Research has examined declining NAD+ availability across ageing models, the competition between PARP activity and sirtuin activity for a shared pool, and salvage pathway flux through NAMPT. Studies of mitochondrial function, DNA repair capacity and circadian metabolic regulation all intersect at this point.
This listing supplies 500mg of lyophilized NAD+. The compound is sensitive to hydrolysis and to elevated temperature, so it ships and stores at -20 degrees Celsius and should be reconstituted immediately before use rather than held in solution. Prepared aliquots degrade measurably over repeated freeze-thaw cycles. It is stocked alongside SS-31, which is studied at the same organelle through an unrelated mechanism. For in vitro laboratory research only. Not for human or veterinary use.
- Sirtuin and PARP enzyme activity research
- Cellular redox and energy metabolism studies
- DNA damage response models
- NAD+ salvage pathway and NAMPT flux work
- Age-related metabolic decline investigations
NAD+ specifications
| Form | Lyophilized Powder |
|---|---|
| Storage | Store at -20°C |
| Handling | Reconstitute immediately before use; avoid repeated freeze-thaw |
| Quantity | 500mg / vial |
| Research Use | In vitro laboratory research only |
| Reported Purity | 99% |
Questions about this listing
- What form does NAD+ come in?
Lyophilized Powder The size options listed on this page — 500mg — are what is available, and the vial labelling shown in the product images above is the reference for what a vial contains.
- How should NAD+ be stored?
Store at -20°C. Reconstitute immediately before use; avoid repeated freeze-thaw. Storage requirements differ across the catalog — some listings are refrigerated, others held at -20°C, others at room temperature — so read this row rather than assuming from a neighbouring product.
- Does Savage Labs supply a diluent for NAD+?
Bacteriostatic water is stocked separately in 3mL and 10mL vials. Savage Labs does not specify a reconstitution volume, a working concentration, or a basis for calculating either — those are determined by the protocol the material is used in, not by this catalog.
- What does the 99% figure on this listing mean?
It is the purity reported for this material. It is a reported value rather than one Savage Labs has independently verified for the lot you receive, and it does not describe net peptide content. How peptide purity is reported and net peptide content cover what the number does and does not tell you.
- What documentation is available for NAD+?
Batch-specific certificates of analysis and test methods on request. Confirm that any report matches the lot you intend to order — reading a peptide certificate of analysis covers which field answers which question. Ask about documentation for this listing, or see the full FAQ for ordering, shipping and returns.
- What else is grouped with NAD+?
It is catalogued under Anti-Aging, where the category page describes what separates the compounds in the group.
Ordering, payment, shipping and returns are answered on the full FAQ.
References
The published work the description above draws on. These are indexed records, not Savage Labs documentation, and none of them establishes a use for NAD+ in people or animals. For records covering the material itself, ask about batch documentation.
- Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes — Antioxid Redox Signal (2019) · PMID 29634344
- NAD⁺ circuits in aging, tissue repair and fibrosis — Ageing Res Rev (2026) · PMID 42607935
